4-Piperidone → 1-(5-Ethylpyrimidin-2-yl)piperidin-4-one

HRID 1928594Notes

Reaction equation

[NH:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.Cl[C:9]1[N:14]=[CH:13][C:12]([CH2:15][CH3:16])=[CH:11][N:10]=1>>[CH2:15]([C:12]1[CH:11]=[N:10][C:9]([N:1]2[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]2)=[N:14][CH:13]=1)[CH3:16]

Participants

Reactant 2

HCID 337214-Piperidone

HCID 35727632-Chloro-5-ethylpyrimidine

Product 1

HCID 577083691-(5-Ethylpyrimidin-2-yl)piperidin-4-one

Procedure

The title compound was synthesized from piperidin-4-one and 2-chloro-5-ethylpyrimidine manner similar to that described in Example 9.

Sources & evidence

ORD record: ord-a6d55a8cdce74a4a81fbc0f947d408e3
Source dataset: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08183381B2

Reaction notes

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