HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → (1-(1-(5-Ethylpyrimidin-2-yl)piperidin-4-yl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | ethyl 1-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate | HCID 57708422 | — |
| Product | (1-(1-(5-Ethylpyrimidin-2-yl)piperidin-4-yl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanol | HCID 57708404 | — |
Reaction Steps
The title compound was synthesized using ethyl 1-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate and sodium borohydride in a manner similar to that described in Example 66, Step 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183381B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-ddc3b1996ad145f2aed1d1f54e70c5af |
| Source note | uspto-grants-2012_05 |