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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1928721Generated: October 30, 2026

N,N-Dimethylethylenediamine → 1-(2-Dimethylamino-ethyl)-3-[2-((R)-indan-1-ylamino)-quinolin-6-yl]-urea

https://huagongshe.com/reaction/1928721

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-DimethylethylenediamineHCID 66053—
ReactantTriphosgeneHCID 94429—
Reactant(R)-N2-Indan-1-yl-quinoline-2,6-diamineHCID 57860958—
Product1-(2-Dimethylamino-ethyl)-3-[2-((R)-indan-1-ylamino)-quinolin-6-yl]-ureaHCID 44217471—

Reaction Steps

The title compound was prepared in accordance with the general method 4 described in example 16 from bis(trichloromethyl) carbonate, 2-dimethylamino-ethylamine and (R)—N2-indan-1-yl-quinoline-2,6-diamine; MS: m/e=390.5 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183380B2
Source datasetuspto-grants-2012_05
ORD IDord-00745c5e26c140caa91af5bd183a7409
Source noteuspto-grants-2012_05