HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphosgene → 1-[2-((R)-Indan-1-ylamino)-quinolin-6-yl]-3-(tetrahydro-pyran-4-yl)-urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphosgene | HCID 94429 | — |
| Reactant | 4-Aminotetrahydropyran | HCID 419223 | — |
| Reactant | (R)-N2-Indan-1-yl-quinoline-2,6-diamine | HCID 57860958 | — |
| Product | 1-[2-((R)-Indan-1-ylamino)-quinolin-6-yl]-3-(tetrahydro-pyran-4-yl)-urea | HCID 44217470 | — |
Reaction Steps
The title compound was prepared in accordance with the general method 4 described in example 16 from bis(trichloromethyl) carbonate, 4-aminotetrahydropyran and (R)—N2-indan-1-yl-quinoline-2,6-diamine; MS: m/e=403.5 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183380B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-eeed91b3f1e94eb68d899d322af62e75 |
| Source note | uspto-grants-2012_05 |