Cyclopropylamine → HCID 44217468, compound

HRID 1928724Notes

Reaction equation

HRID 1928724 reaction equation
[C:1](=[O:12])(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.[CH:13]1([NH2:16])[CH2:15][CH2:14]1.[C@H:17]1([NH:26][C:27]2[CH:36]=[CH:35][C:34]3[C:29](=[CH:30][CH:31]=[C:32]([NH2:37])[CH:33]=3)[N:28]=2)[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH2:19][CH2:18]1>>[CH:13]1([NH:16][C:1]([NH:37][C:32]2[CH:33]=[C:34]3[C:29](=[CH:30][CH:31]=2)[N:28]=[C:27]([NH:26][C@H:17]2[C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[CH2:19][CH2:18]2)[CH:36]=[CH:35]3)=[O:12])[CH2:15][CH2:14]1

Participants

4

Reactant 3

HCID 69828CyclopropylamineHCID 94429TriphosgeneHCID 57860958(R)-N2-Indan-1-yl-quinoline-2,6-diamine

Product 1

HCID 44217468HCID 44217468, compound

Procedure

The title compound was prepared in accordance with the general method 4 described in example 16 from bis(trichloromethyl) carbonate, cyclopropylamine and (R)—N2-indan-1-yl-quinoline-2,6-diamine; MS: m/e=359.5 (M+H+).

Sources & evidence

ORD record
ord-f0d4d5e2212440228f74e11d79be6fa6
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

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