Cyclopropanemethanamine → HCID 44217308, compound

HRID 1928726Notes

Reaction equation

HRID 1928726 reaction equation
[C:1](=[O:12])(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.[NH2:13][CH2:14][CH:15]1[CH2:17][CH2:16]1.[C@H:18]1([NH:27][C:28]2[CH:37]=[CH:36][C:35]3[C:30](=[CH:31][CH:32]=[C:33]([NH2:38])[CH:34]=3)[N:29]=2)[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:20][CH2:19]1>>[CH:15]1([CH2:14][NH:13][C:1]([NH:38][C:33]2[CH:34]=[C:35]3[C:30](=[CH:31][CH:32]=2)[N:29]=[C:28]([NH:27][C@H:18]2[C:26]4[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=4)[CH2:20][CH2:19]2)[CH:37]=[CH:36]3)=[O:12])[CH2:17][CH2:16]1

Participants

4

Reactant 3

HCID 75646CyclopropanemethanamineHCID 94429TriphosgeneHCID 57860958(R)-N2-Indan-1-yl-quinoline-2,6-diamine

Product 1

HCID 44217308HCID 44217308, compound

Procedure

The title compound was prepared in accordance with the general method 4 described in example 16 from bis(trichloromethyl) carbonate, aminomethyl cyclopropane and (R)—N2-indan-1-yl-quinoline-2,6-diamine; MS: m/e=373.5 (M+H+).

Sources & evidence

ORD record
ord-9fc3662e080044c3b1f2bc5b4af7f9e1
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

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