Triphosgene → HCID 44218263, compound

HRID 1928729Notes

Reaction equation

HRID 1928729 reaction equation
[C:1](=[O:12])(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.[CH2:13]([NH:15][CH:16]1[CH2:21][CH2:20][CH:19]([OH:22])[CH2:18][CH2:17]1)[CH3:14].[C@H:23]1([NH:32][C:33]2[CH:42]=[CH:41][C:40]3[C:35](=[CH:36][CH:37]=[C:38]([NH2:43])[CH:39]=3)[N:34]=2)[C:31]2[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=2)[CH2:25][CH2:24]1>>[CH2:13]([N:15]([CH:16]1[CH2:21][CH2:20][CH:19]([OH:22])[CH2:18][CH2:17]1)[C:1]([NH:43][C:38]1[CH:39]=[C:40]2[C:35](=[CH:36][CH:37]=1)[N:34]=[C:33]([NH:32][C@H:23]1[C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[CH2:25][CH2:24]1)[CH:42]=[CH:41]2)=[O:12])[CH3:14]

Participants

4

Reactant 3

HCID 94429TriphosgeneHCID 201345754-(Ethylamino)cyclohexanolHCID 57860958(R)-N2-Indan-1-yl-quinoline-2,6-diamine

Product 1

HCID 44218263HCID 44218263, compound

Procedure

The title compound was prepared in accordance with the general method 4 described in example 16 from bis(trichloromethyl) carbonate, 4-ethylamino-cyclohexanol and (R)—N2-indan-1-yl-quinoline-2,6-diamine; MS: m/e=445.7 (M+H+).

Sources & evidence

ORD record
ord-fe1bd6ff902d4c31af84e8e3b3ad77a0
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

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