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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1928768Generated: November 1, 2026

Dimethylsulphamoyl chloride → Rac-n'-{2-[(8-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)amino]quinolin-6-yl}-n,n-dimethylsulfamide

https://huagongshe.com/reaction/1928768

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylsulphamoyl chlorideHCID 83372—
ReactantRac-n2-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-quinoline-2,6-diamineHCID 57860959—
ProductRac-n'-{2-[(8-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)amino]quinolin-6-yl}-n,n-dimethylsulfamideHCID 68640292—

Reaction Steps

The title compound was prepared in accordance with the general method described in example 66 from dimethylsulfamoyl chloride and rac-N2-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-quinoline-2,6-diamine; MS: m/e=427.3 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183380B2
Source datasetuspto-grants-2012_05
ORD IDord-b945c237676b45d991ef8daff099fe6d
Source noteuspto-grants-2012_05