HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-N2-Indan-1-yl-quinoline-2,6-diamine → N-cyclopropyl-N'-{2-[(1R)-2,3-dihydro-1H-inden-1-ylamino]quinolin-6-yl}-N-methylsulfamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-N2-Indan-1-yl-quinoline-2,6-diamine | HCID 57860958 | — |
| Reactant | 3-(cyclopropyl-methyl-sulfamoyl)-1-methyl-3-H-imidazol-1-ium trifluoromethanesulfonate | HCID 86634171 | — |
| Product | N-cyclopropyl-N'-{2-[(1R)-2,3-dihydro-1H-inden-1-ylamino]quinolin-6-yl}-N-methylsulfamide | HCID 68910936 | — |
Reaction Steps
The title compound was prepared in accordance with step C of the general method described in example 76 from 3-(cyclopropyl-methyl-sulfamoyl)-1-methyl-3-H-imidazol-1-ium trifluoromethanesulfonate and (R)—N2-indan-1-yl-quinoline-2,6-diamine; MS: m/e=409.7 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183380B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-d3637ba31445431eb817eaf195b66d83 |
| Source note | uspto-grants-2012_05 |