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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1928810Generated: November 1, 2026

1-Isopropylpiperazine → HCID 44218425, compound

https://huagongshe.com/reaction/1928810

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-IsopropylpiperazineHCID 78013—
ReactantTriphosgeneHCID 94429—
Reactant(R)-N2-Indan-1-yl-quinoline-2,6-diamineHCID 57860958—
ProductHCID 44218425HCID 44218425—

Reaction Steps

The title compound was prepared in accordance with the general method 4 described in example 16 from bis(trichloromethyl) carbonate (44 mg, 0.16 mmol), commercially available 1-(2-propyl)-piperazine (47 mg, 0.363 mmol) and (R)—N2-indan-1-yl-quinoline-2,6-diamine (100 mg, 0.363 mmol); obtained as a white solid (32 mg, 21%); MS: m/e=430.4 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183380B2
Source datasetuspto-grants-2012_05
ORD IDord-c718996f71d44853a36430646164ea02
Source noteuspto-grants-2012_05