127595-09-9 → HCID 44217149, compound

HRID 1928853Notes

Reaction equation

HRID 1928853 reaction equation
Cl.Cl[C:3]([O:5][CH:6]1[CH2:11][CH2:10][N:9]([CH3:12])[CH2:8][CH2:7]1)=[O:4].[C@H:13]1([NH:22][C:23]2[CH:32]=[CH:31][C:30]3[C:25](=[CH:26][CH:27]=[C:28]([NH2:33])[CH:29]=3)[N:24]=2)[C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH2:15][CH2:14]1>C(N(CC)CC)C>[CH3:12][N:9]1[CH2:10][CH2:11][CH:6]([O:5][C:3](=[O:4])[NH:33][C:28]2[CH:29]=[C:30]3[C:25](=[CH:26][CH:27]=2)[N:24]=[C:23]([NH:22][C@H:13]2[C:21]4[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=4)[CH2:15][CH2:14]2)[CH:32]=[CH:31]3)[CH2:7][CH2:8]1

Participants

4

Reactant 2

HCID 14762751127595-09-9HCID 57860958(R)-N2-Indan-1-yl-quinoline-2,6-diamine

Product 1

HCID 44217149HCID 44217149, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The title compound was prepared in accordance with the general method 11 described in example 138 from triethylamine, 4-chlorocarbonyloxy-1-methylpiperidine hydrochloride (CAS no: 127595-09-9) and (R)—N2-indan-1-yl-quinoline-2,6-diamine; MS: m/e=215.3 (M+H+).

Sources & evidence

ORD record
ord-45231d52765944c0b62ff1e9ad43f25b
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

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