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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1928873Generated: October 31, 2026

(4-Methylpiperazin-1-yl)acetic acid → HCID 68913013, compound

https://huagongshe.com/reaction/1928873

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Methylpiperazin-1-yl)acetic acidHCID 2762732—
ReactantHCID 68631849HCID 68631849—
ProductHCID 68913013HCID 68913013—

Reaction Steps

The title compound was prepared from rac-N2-(4-methoxy-2,3-dihydro-benzofuran-3-yl)-quinoline-2,6-diamine (Example 173) (150 mg, 0.59 mmol) and commercially available (4-methyl-piperazin-1-yl)-acetic acid (77 mg, 0.68 mmol) in accordance with the general method 14 described in example 119 and was obtained as an off-white solid (210 mg, 96%); MS: m/e=448.3 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183380B2
Source datasetuspto-grants-2012_05
ORD IDord-e27e9e7947d241f1bb4c28d96b71a57f
Source noteuspto-grants-2012_05