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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1928874Generated: October 31, 2026

(4-Methylpiperazin-1-yl)acetic acid → HCID 68915596, compound

https://huagongshe.com/reaction/1928874

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Methylpiperazin-1-yl)acetic acidHCID 2762732—
ReactantHCID 68913590HCID 68913590—
ProductHCID 68915596HCID 68915596—

Reaction Steps

The title compound was prepared from rac-N2-(4-ethoxy-2,3-dihydro-benzofuran-3-yl)-quinoline-2,6-diamine (Example 175) (200 mg, 0.49 mmol) and commercially available (4-methyl-piperazin-1-yl)-acetic acid (74 mg, 0.65 mmol) in accordance with the general method 14 described in example 119 and was obtained as an off-white solid (200 mg, 93%); MS: m/e=462.2 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183380B2
Source datasetuspto-grants-2012_05
ORD IDord-789cd6c05a5344f8916a9ec955c1c625
Source noteuspto-grants-2012_05