HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrophenyl chloroformate → HCID 68633190, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrophenyl chloroformate | HCID 82129 | — |
| Reactant | 2-(4-Aminopiperidin-1-yl)ethan-1-ol | HCID 15733445 | — |
| Reactant | Rac-n2-(7-methoxy-indan-1-yl)-quinoline-2,6-diamine | HCID 57860964 | — |
| Product | HCID 68633190 | HCID 68633190 | — |
Reaction Steps
The title compound was prepared from rac-N2-(7-methoxy-indan-1-yl)-quinoline-2,6-diamine (Example 172) (200 mg, 0.655 mmol), 4-nitrophenyl chloroformate (132 mg, 0.655 mmol) and commercially available 4-amino-1-piperidine ethanol (94 mg, 0.655 mmol) in accordance with the general method 4 described in example 170 step C and was obtained as an off-white solid (160 mg, 26%); MS: m/e=476.2 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183380B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-1ad8107e4ce24e8db3c6faddd340acbb |
| Source note | uspto-grants-2012_05 |