Isopropanol → 4-(1-(pyridin-4-yl)-1H-imidazol-2-yl)phenol

HRID 192892Notes

Reaction equation

[B:42]([Br:43])([Br:44])[Br:45].[CH3:1][n:2]1[c:3](-[c:4]2[cH:5][cH:6][c:7]([OH:8])[cH:9][cH:10]2)[c:11](-[c:12]2[cH:13][cH:14][n:15][cH:16][cH:17]2)[n:18][n:19]1.[CH3:23][O:24][c:25]1[cH:26][cH:27][c:28](-[c:31]2[n:32](-[c:36]3[cH:37][cH:38][n:39][cH:40][cH:41]3)[cH:33][cH:34][n:35]2)[cH:29][cH:30]1.[CH3:46][CH:47]([OH:48])[CH3:49].[Cl:20][CH2:21][Cl:22]>>[OH:24][c:25]1[cH:26][cH:27][c:28](-[c:31]2[n:32](-[c:36]3[cH:37][cH:38][n:39][cH:40][cH:41]3)[cH:33][cH:34][n:35]2)[cH:29][cH:30]1

Participants

Reactant 5

HCID 3776Isopropanol

HCID 6344Dichloromethane

HCID 25134Boron tribromide

HCID 571501814-(2-(4-methoxyphenyl)-1H-imidazol-1-yl)pyridine

HCID 1363758384-(3-methyl-5-(pyridin-4-yl)-3H-1,2,3-triazol-4-yl)phenol

Product 1

HCID 1363758214-(1-(pyridin-4-yl)-1H-imidazol-2-yl)phenol

Sources & evidence

ORD record: ord-35da2ccab88d4107b550142789f24a92
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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