HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59600181, compound → 4-Cyclobutylmethoxy-1H-indole-2-carboxylic acid {1-[2-(3-(R)-hydroxy-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59600181 | HCID 59600181 | — |
| Reactant | 8-[2-(4-Amino-piperidin-1-yl)-ethyl]-8-aza-bicyclo[3.2.1]octan-3-ol trihydrochloride | HCID 66841574 | — |
| Product | 4-Cyclobutylmethoxy-1H-indole-2-carboxylic acid {1-[2-(3-(R)-hydroxy-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amide | HCID 59600131 | — |
Reaction Steps
This compound is synthesized analogously to Example 1 from 4-Cyclobutylmethoxy-1H-indole-2-carboxylic acid 82 (preparation see Example 22) and amine 24.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183366B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-6cf68b6ab89b45ff9a294c5a98b111ee |
| Source note | uspto-grants-2012_05 |