HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyclobutylmethoxy-1H-indole-2-carboxylic acid → 4-Cyclobutylmethoxy-1H-indole-2-carboxylic acid {1-[(S)-2-(4-hydroxy-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyclobutylmethoxy-1H-indole-2-carboxylic acid | HCID 59152682 | — |
| Reactant | 1-[(S)-2-(4-Amino-piperidin-1-yl)-1-methyl-ethyl]-piperidin-4-ol trihydrochloride | HCID 66841433 | — |
| Product | 4-Cyclobutylmethoxy-1H-indole-2-carboxylic acid {1-[(S)-2-(4-hydroxy-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide | HCID 59600211 | — |
Reaction Steps
This compound is synthesized analogously to example 1 from 4-cyclobutylmethoxy-1H-indole-2-carboxylic acid, 82 (see example 22) and amine 50.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183366B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-4bf7b43f64e640a5b81ad22decb5015a |
| Source note | uspto-grants-2012_05 |