HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3,3-dimethyl-butoxy)-1H-indole-2-carboxylic acid → 4-(3,3-Dimethyl-butoxy)-1H-indole-2-carboxylic acid {1-[2-(4-hydroxy-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amide dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3,3-dimethyl-butoxy)-1H-indole-2-carboxylic acid | HCID 66841572 | — |
| Reactant | HCID 66841786 | HCID 66841786 | — |
| Product | 4-(3,3-Dimethyl-butoxy)-1H-indole-2-carboxylic acid {1-[2-(4-hydroxy-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amide dihydrochloride | HCID 66841315 | — |
Reaction Steps
This compound is synthesized analogously to Example 1 from 4-(3,3-dimethyl-butoxy)-1H-indole-2-carboxylic acid (92) (preparation see below) and amine 21.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183366B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-055b7c1b1ace4f0b985bf5197a12eb40 |
| Source note | uspto-grants-2012_05 |