HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3-Dimethyl-1-butanol → 4-(3,3-dimethyl-butoxy)-1H-indole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3-Dimethyl-1-butanol | HCID 12233 | — |
| Reactant | 4-(2,2-Dimethyl-propoxy)-1H-indole-2-carboxylic acid | HCID 66841536 | — |
| Product | 4-(3,3-dimethyl-butoxy)-1H-indole-2-carboxylic acid | HCID 66841572 | — |
Reaction Steps
This compound is synthesized analogously to (85) from 3,3-dimethyl-butan-1-ol. Yield: 1.1 g (100%). MS (ESI): 260 [M−H]−, 1H-NMR (DMSO-d6): δ (ppm) 12.8 (s, 1H), 11.65 (s, 1H), 7.12 (dd, 1H), 6.98 (s, 1H), 6.95 (d, 1H), 6.52 (d, 1H), 4.13 (t, 2H), 1.75 (t, 2H), 1.0 (s, 9H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183366B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-0fd3bdcd053244e6a6e5f0c07f9df8af |
| Source note | uspto-grants-2012_05 |