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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1929099Generated: October 31, 2026

4-(6-fluoro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid → 4-(6-Fluoro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[2-(4-hydroxy-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amide dihydrochloride

https://huagongshe.com/reaction/1929099

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(6-fluoro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acidHCID 66841531—
ReactantHCID 66841786HCID 66841786—
Product4-(6-Fluoro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[2-(4-hydroxy-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amide dihydrochlorideHCID 66841543—

Reaction Steps

This compound is synthesized from 4-(6-fluoro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid (106, see example 55) and amine 21 analogously to the method described in example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183366B2
Source datasetuspto-grants-2012_05
ORD IDord-1efb459801a7489da26c131f115bf3ee
Source noteuspto-grants-2012_05