Tetrahydrofuran → 1-(tert-Butoxycarbonyl)-4-hydroxy-4-(2-ethyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)piperidine
Reaction equation
[Br:1][c:2]1[c:3]([CH2:11][CH3:12])[n:4][n:5]2[c:6]1[CH2:7][CH2:8][CH2:9][CH2:10]2.[C:13]([Li:14])([CH3:15])([CH3:16])[CH3:17].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[O:18]=[C:19]1[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:23][CH2:24]1>>[c:2]1([C:19]2([OH:18])[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:23][CH2:24]2)[c:3]([CH2:11][CH3:12])[n:4][n:5]2[c:6]1[CH2:7][CH2:8][CH2:9][CH2:10]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-001b490acc0d40a283f07539f6115532
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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