HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[(S)-2-(4-Amino-piperidin-1-yl)-1-methyl-ethyl]-piperidin-4-ol trihydrochloride → 4-(4-Ethoxy-phenyl)-1H-indole-2-carboxylic acid {1-[(S)-2-(4-hydroxy-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[(S)-2-(4-Amino-piperidin-1-yl)-1-methyl-ethyl]-piperidin-4-ol trihydrochloride | HCID 66841433 | — |
| Reactant | 4-(4-ethoxy-phenyl)-1H-indole-2-carboxylic acid | HCID 66841435 | — |
| Product | 4-(4-Ethoxy-phenyl)-1H-indole-2-carboxylic acid {1-[(S)-2-(4-hydroxy-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide | HCID 59600238 | — |
Reaction Steps
This compound is synthesized analogously to example 1 from 4-(4-ethoxy-phenyl)-1H-indole-2-carboxylic acid, (preparation analogously to 128, see example 141) and amine 50.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183366B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-6cefe4df3ea34972903a6a62293c8572 |
| Source note | uspto-grants-2012_05 |