1-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochloride → HCID 86649943, compound

HRID 1929189Notes

Reaction equation

HRID 1929189 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([O:8][C:9]2[CH:17]=[CH:16][CH:15]=[C:14]3[C:10]=2[CH:11]=[C:12]([C:18]([OH:20])=O)[NH:13]3)[CH:5]=[CH:4][CH:3]=1.Cl.Cl.Cl.[N:24]1([CH2:31][CH2:32][N:33]2[CH2:38][CH2:37][CH:36]([NH2:39])[CH2:35][CH2:34]2)[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1>>[N:24]1([CH2:31][CH2:32][N:33]2[CH2:34][CH2:35][CH:36]([NH:39][C:18]([C:12]3[NH:13][C:14]4[C:10]([CH:11]=3)=[C:9]([O:8][C:6]3[CH:5]=[CH:4][CH:3]=[C:2]([Cl:1])[N:7]=3)[CH:17]=[CH:16][CH:15]=4)=[O:20])[CH2:37][CH2:38]2)[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1

Participants

3

Reactant 2

HCID 668413931-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochlorideHCID 866499444-(6-Chloro-pyridin-2-yloxy)-1H-indole-2-carboxylic acid

Product 1

HCID 86649943HCID 86649943, compound

Procedure

This compound is synthesized analogously to Example 1 from 4-(6-Chloro-pyridin-2-yloxy)-1H-indole-2-carboxylic acid 157 (preparation see below) and amine 5.

Sources & evidence

ORD record
ord-adadd0fb74a54d369bf84a4aa9cf35a1
Source dataset
uspto-grants-2012_05
Patent number
US08183366B2

Reaction notes

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