HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochloride → 4-(6-Chloro-pyridin-2-yloxy)-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochloride | HCID 66841393 | — |
| Reactant | 4-(6-Chloro-pyridin-2-yloxy)-1H-indole-2-carboxylic acid | HCID 86649944 | — |
| Product | 4-(6-Chloro-pyridin-2-yloxy)-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amide | HCID 86649943 | — |
Reaction Steps
This compound is synthesized analogously to Example 1 from 4-(6-Chloro-pyridin-2-yloxy)-1H-indole-2-carboxylic acid 157 (preparation see below) and amine 5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183366B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-adadd0fb74a54d369bf84a4aa9cf35a1 |
| Source note | uspto-grants-2012_05 |