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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1929239Generated: October 30, 2026

4-Isobutoxy-benzo[b]thiophene-2-carboxylic acid → 4-Isobutoxy-benzo[b]thiophene-2-carboxylic acid [1-(2-piperidin-1-yl-ethyl)-piperidin-4-y]-amide

https://huagongshe.com/reaction/1929239

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Isobutoxy-benzo[b]thiophene-2-carboxylic acidHCID 59600259—
Reactant1-(2-(Piperidin-1-yl)ethyl)piperidin-4-amine trihydrochlorideHCID 66841362—
Product4-Isobutoxy-benzo[b]thiophene-2-carboxylic acid [1-(2-piperidin-1-yl-ethyl)-piperidin-4-y]-amideHCID 59600196—

Reaction Steps

This compound is synthesized from compound 202 and amine 1 analogously to the method described in Example 178.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183366B2
Source datasetuspto-grants-2012_05
ORD IDord-12e617cbb9e242dabad7a47ce3bb6078
Source noteuspto-grants-2012_05