Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 10848710, compound

HRID 1929434Notes

Reaction equation

HRID 1929434 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([N+:9]([O-:11])=[O:10])=[CH:4][C:3]=1[OH:12].Br[C:14]([CH3:21])([CH3:20])[C:15](OCC)=[O:16]>>[Cl:8][C:6]1[C:5]([N+:9]([O-:11])=[O:10])=[CH:4][C:3]2[O:12][C:14]([CH3:21])([CH3:20])[C:15](=[O:16])[NH:1][C:2]=2[CH:7]=1

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 38948482-Amino-4-chloro-5-nitrophenol

Product 1

HCID 10848710HCID 10848710, compound

Procedure

2-amino-4-chloro-5-nitrophenol (10.0 g) and ethyl α-bromoisobutyrate (7.4 mL) were treated in the same manner as described in Reference Example 1(1) to give 6-chloro-2,2-dimethyl-7-nitro-2H-1,4-benzoxazin-3(4H)-one (6.82 g) as a pale brown powder.

Sources & evidence

ORD record
ord-b479097946bb49d9bafea2ddfbc30b79
Source dataset
uspto-grants-2012_05
Patent number
US08188073B2

Reaction notes

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