HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzophenone imine → HCID 58155237, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzophenone imine | HCID 136809 | — |
| Reactant | HCID 58155298 | HCID 58155298 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 58155237 | HCID 58155237 | — |
Reaction Steps
In an analogous manner to that described for the preparation of Building block A [f)], the palladium-catalyzed amination of (RS)-5-(5-bromo-2-fluoro-phenyl)-5-cyclopropyl-morpholin-3-one with benzophenonimine yielded the (RS)-5-[5-(benzhydrylidene-amino)-2-fluoro-phenyl]-5-cyclopropyl-morpholin-3-one as a yellow foam. Mass (calculated) C26H23FN2O2 [414.478]; (found) [M+H]+=415.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188079B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-a09eb102d4b04d0d86b7fa92a5e30ff5 |
| Source note | uspto-grants-2012_05 |