HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (R)-5-(5-Amino-2-fluoro-phenyl)-5-methyl-morpholine-3-thione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (R)-5-[5-(Benzhydrylidene-amino)-2-fluoro-phenyl]-5-methyl-morpholine-3-thione | HCID 86651220 | — |
| Product | (R)-5-(5-Amino-2-fluoro-phenyl)-5-methyl-morpholine-3-thione | HCID 58155253 | — |
Reaction Steps
In a manner analogous to the preparation of Building block E the hydrolysis of (R)-5-[5-(benzhydrylidene-amino)-2-fluoro-phenyl]-5-methyl-morpholine-3-thione with hydrochloric acid yielded the title compound as a light brown foam. Mass (calculated) C11H13FN2OS [240.301]; (found) [M+H]+=241.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188079B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-2e887b1b822049b1a95b4981e673903e |
| Source note | uspto-grants-2012_05 |