5-(2,2,2-Trifluoroethoxy)pyridine-2-carboxylic acid → HCID 86651227, compound

Participants

Reaction Steps

In a reaction analogous to that described in example 6 (method B), the condensation of 5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (CAS 881409-53-6) with Building block F, (RS)-5-(3-amino-phenyl)-5-methyl-morpholine-3-thione, yielded the title compound as a as light yellow oil (64% of theory). Mass (calculated) C19H18F3N3O3S [425.43]; (found) [M+H]+=426.

Provenance & Evidence