HCID 68973103, compound → HCID 68972653, compound

HRID 1929536Notes

Reaction equation

HRID 1929536 reaction equation
[CH3:1][N:2]([CH3:25])[C:3]([C:6]1[N:10]2[CH2:11][CH2:12][N:13](C(OCC3C=CC=CC=3)=O)[CH2:14][C:9]2=[N:8][N:7]=1)([CH3:5])[CH3:4]>CO.[Pd]>[CH3:25][N:2]([CH3:1])[C:3]([C:6]1[N:10]2[CH2:11][CH2:12][NH:13][CH2:14][C:9]2=[N:8][N:7]=1)([CH3:5])[CH3:4]

Participants

4

Reactant 1

HCID 68973103HCID 68973103, compound

Product 1

HCID 68972653HCID 68972653, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of P5 (0.12 mmol) and Pd/C (10%, 22 mg) in MeOH (0.2 M) was stirred under H2 atmosphere overnight. The catalyst was filtered off and the solvent removed under reduced pressure to provide a crude oil used as such in the next step. MS (ES) C10H19N5 required: 209. found: 210 (M+H)+.

Workup

  1. filtrationThe catalyst was filtered off
  2. customthe solvent removed under reduced pressure
  3. customto provide a crude oil

Sources & evidence

ORD record
ord-8834e859aae441f7abe7f97acbd1c0cf
Source dataset
uspto-grants-2012_05
Patent number
US08188084B2

Reaction notes

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