Ammonia → HCID 69277495, compound

HRID 1929552Notes

Reaction equation

[CH3:1][O:2][C:3]1[C:8]([O:9][CH3:10])=[CH:7][C:6]([CH:11]=[C:12]([C:23]2[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[CH:25][CH:24]=2)[C:13]([N:15]2[CH2:19][CH2:18][CH2:17][CH:16]2[C:20]([OH:22])=[O:21])=O)=[C:5]([N+:31]([O-:33])=[O:32])[CH:4]=1.N>>[CH3:1][O:2][C:3]1[C:8]([O:9][CH3:10])=[CH:7][C:6]([CH:11]=[C:12]([C:23]2[CH:24]=[CH:25][C:26]([O:29][CH3:30])=[CH:27][CH:28]=2)[CH2:13][N:15]2[CH2:19][CH2:18][CH2:17][CH:16]2[C:20]([OH:22])=[O:21])=[C:5]([N+:31]([O-:33])=[O:32])[CH:4]=1

Participants

Reactant 2

HCID 222Ammonia

HCID 68869396HCID 68869396, compound

Product 1

HCID 69277495HCID 69277495, compound

Procedure

General procedure d from 39 (90%); brown syrup; 1H NMR (400.13 MHz) δ 7.61 (s, 1H), 7.24 (d, J=4 Hz, 2H), 7.01 (s, 1H), 6.77 (d, J=4 Hz, 2H), 6.64 (s, 1H), 4.36 (d, J=7 Hz, 2H), 3.89 (s, 3H), 3.72 (t, J=7 Hz, 1H), 3.69 (s, 3H), 3.42 (s, 3H), 3.24 (m, 2H), 2.18 (m, 2H), 1.84 (m, 2H); MS (DCI/NH3) m/e: 429 (M+H)+.

Sources & evidence

ORD record: ord-f250dc2eba9f4149b4efd43d9975ed2c
Source dataset: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08188089B2

Reaction notes

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