Ammonia → HCID 69276492, compound

HRID 1929553Notes

Reaction equation

[CH3:1][O:2][C:3]1[C:8]([O:9][CH3:10])=[CH:7][C:6]([CH:11]=[C:12]([C:22]2[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=2)[CH2:13][N:14]2[CH2:18][CH2:17][CH2:16][CH:15]2[C:19](O)=[O:20])=[C:5]([N+:30]([O-:32])=[O:31])[CH:4]=1.N>>[CH3:1][O:2][C:3]1[C:8]([O:9][CH3:10])=[CH:7][C:6]([CH:11]=[C:12]([C:22]2[CH:23]=[CH:24][C:25]([O:28][CH3:29])=[CH:26][CH:27]=2)[CH2:13][N:14]2[CH2:18][CH2:17][CH2:16][CH:15]2[CH2:19][OH:20])=[C:5]([N+:30]([O-:32])=[O:31])[CH:4]=1

Participants

Reactant 2

HCID 222Ammonia

HCID 69277495HCID 69277495, compound

Product 1

HCID 69276492HCID 69276492, compound

Procedure

General procedure f from 40 (90%); dark oil; 1H NMR (400.13 MHz) δ 7.59 (s, 1H), 7.23 (d, J=4 Hz, 2H), 7.00 (s, 1H), 6.71 (d, J=4 Hz, 2H), 6.23 (s, 1H), 4.17 (d, J=7 Hz, 2H), 3.89 (s, 3H), 3.78 (d, J=7 Hz, 2H), 3.69 (s, 3H), 3.58 (m, 1H), 3.41 (s, 3H), 3.16 (m, 2H), 1.91 (m, 2H), 1.80 (m, 2H); MS (DCI/NH3) m/e: 415 (M+H)+.

Sources & evidence

ORD record: ord-9df914a6bab642cd8289c4b4948347cc
Source dataset: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08188089B2

Reaction notes

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