HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Fluoro-4-hydroxy-naphthalen-2-yl)-acetic acid methyl ester → 7-Fluoro-3-methoxycarbonylmethyl-naphthalene-1-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Fluoro-4-hydroxy-naphthalen-2-yl)-acetic acid methyl ester | HCID 20335012 | — |
| Reactant | 7-Fluoro-3-methoxycarbonylmethyl-2-methyl-naphthalene-1-carboxylic acid | HCID 59326734 | — |
| Product | 7-Fluoro-3-methoxycarbonylmethyl-naphthalene-1-carboxylic acid | HCID 59326730 | — |
Reaction Steps
Starting with (6-fluoro-4-hydroxy-naphthalen-2-yl)-acetic acid methyl ester, using the method analogous to the one described for 7-fluoro-3-methoxycarbonylmethyl-2-methyl-naphthalene-1-carboxylic acid, 7-fluoro-3-methoxycarbonylmethyl-naphthalene-1-carboxylic acid (80 mg) was obtained as a light brown viscous oil. MS cald. for C14H10FO4 262, obsd. (ESI+) [(M+H)+] 263.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188090B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-4092a67a77444c4fbdc7628976b8764c |
| Source note | uspto-grants-2012_05 |