HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-trifluoromethyl-phenoxy)-acetaldehyde → HCID 66734144, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-trifluoromethyl-phenoxy)-acetaldehyde | HCID 11252687 | — |
| Reactant | HCID 66734063 | HCID 66734063 | — |
| Product | HCID 66734144 | HCID 66734144 | — |
Reaction Steps
According to the general procedure (GP10), microwave-assisted Pictet-Spengler reaction (60 W; 140° C.; 6.5 bars; 10 min.) between 2-(2-ethyl-4-iodo-imidazol-1-yl)-ethylamine (3.880 mmol) and (3-trifluoromethyl-phenoxy)-acetaldehyde (0.792 g; 3.880 mmol) afforded 3-ethyl-1-iodo-8-(3-trifluoromethyl-phenoxymethyl)-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188082B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-127d2da263874f3895574f9cd9cf1ff8 |
| Source note | uspto-grants-2012_05 |