Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1929683Generated: October 31, 2026

2-(2,4-Dimethyl-1H-imidazol-1-yl)ethanamine → 8-[2-(2,4-Dimethoxyphenyl)ethyl]-1,3-dimethyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine

https://huagongshe.com/reaction/1929683

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2,4-Dimethyl-1H-imidazol-1-yl)ethanamineHCID 18460700—
Reactant3-(2,4-Dimethoxyphenyl)propanalHCID 21859728—
Product8-[2-(2,4-Dimethoxyphenyl)ethyl]-1,3-dimethyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazineHCID 66733171—

Reaction Steps

Prepared according to the previously described general procedure (GP11) by reaction of 2-(2,4-dimethyl-imidazol-1-yl)-ethylamine with 3-(2,4-dimethoxy-phenyl)-propionaldehyde. LC-MS: tR=0.59 min.; [M+H]+=316 g/mol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188082B2
Source datasetuspto-grants-2012_05
ORD IDord-d4fddfa731ee4b339982009e5b46cb58
Source noteuspto-grants-2012_05