HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanemethanol → 5-(4-Fluorophenyl)-6-cyclopropylmethoxy-nicotinic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanemethanol | HCID 75644 | — |
| Reactant | 6-Chloro-5-(4-fluoro-phenyl)-nicotinic acid | HCID 46313827 | — |
| Product | 5-(4-Fluorophenyl)-6-cyclopropylmethoxy-nicotinic acid | HCID 21109721 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 5c, using 6-chloro-5-(4-fluoro-phenyl)-nicotinic acid and (hydroxymethyl)cyclopropane as starting materials, MS (ISP) 286.0 (M−H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188093B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-1d5c3e906541451dba10ae7e4bcda420 |
| Source note | uspto-grants-2012_05 |