HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-4-fluorobenzaldehyde → 7-Chloro-6-fluoroisoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-4-fluorobenzaldehyde | HCID 593866 | — |
| Reactant | 6-Fluoroisoquinoline | HCID 21889847 | — |
| Product | 7-Chloro-6-fluoroisoquinoline | HCID 53418922 | — |
Reaction Steps
Starting from 3-chloro-4-fluoro-benzaldehyde, the title compound was prepared by the same reaction sequence as used for the synthesis of 6-fluoro-isoquinoline (3). Rt=0.77 min (Method A). Detected mass: 182.1/184.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188117B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-0555398550ce4238a785fb9fa39938a4 |
| Source note | uspto-grants-2012_05 |