HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopropane → HCID 57652506, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopropane | HCID 6358 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 57652410 | HCID 57652410 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 57652506 | HCID 57652506 | — |
Reaction Steps
By alkylation of 50 mg of 7-fluoro-4-methyl-6-(piperidin-4-yloxy)-2H-isoquinolin-1-one (22) with isopropylbromide in the presence of triethylamine in DMF at 60° C. 31 mg of 7-Fluoro-6-(1-isopropyl-piperidin-4-yloxy)-4-methyl-2H-isoquinolin-1-one were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188117B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-387b10ac33754b46b3a0c932ff6ff8bd |
| Source note | uspto-grants-2012_05 |