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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1930598Generated: November 1, 2026

Phenylacetyl chloride → 3-(2-phenylacetyl)dihydro-2H-pyran-4(3H)-one

https://huagongshe.com/reaction/1930598

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylacetyl chlorideHCID 7679—
ReactantTetrahydro-4H-pyran-4-oneHCID 121599—
Product3-(2-phenylacetyl)dihydro-2H-pyran-4(3H)-oneHCID 5933377949.4%

Reaction Steps

3-(2-Phenylacetyl)dihydro-2H-pyran-4(3H)-one (0.538 g, 49.4%) was synthesised from tetrahydro-4H-pyran-4-one (0.923 mL, 9.99 mmol) and phenylacetyl chloride (0.660 mL, 4.99 mmol) by the general procedure for the preparation of ketones.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188101B2
Source datasetuspto-grants-2012_05
ORD IDord-9a9d2f0a791a484bb679de8fd6c92e90
Source noteuspto-grants-2012_05