HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrothiopyran-4-one → 3-(2-(4-Fluorophenyl)acetyl)dihydro-2H-thiopyran-4(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrothiopyran-4-one | HCID 66173 | — |
| Reactant | 4-Fluorophenylacetyl chloride | HCID 3744988 | — |
| Product | 3-(2-(4-Fluorophenyl)acetyl)dihydro-2H-thiopyran-4(3H)-one | HCID 59333708 | 78% |
Reaction Steps
3-(2-(4-Fluorophenyl)acetyl)dihydro-2H-thiopyran-4(3H)-one (508 mg, 78%) was obtained from tetrahydrothiopyran-4-one and 4-fluorophenylacetyl chloride by the general procedure for the preparation of diketones. MS (ES+) m/z 253.1 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188101B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-f2fe3d4b049248e9a66d1db1abbcf69e |
| Source note | uspto-grants-2012_05 |