HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59333808, compound → HCID 59333691, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59333808 | HCID 59333808 | — |
| Reactant | HCID 178432900 | HCID 178432900 | — |
| Product | HCID 59333691 | HCID 59333691 | 62% |
Reaction Steps
tert-Butyl 4-(3-methoxybenzyl)-2-(4-(2-methyl-1H-imidazol-1-yl)phenylamino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate (373 mg, 62%) was synthesised from tert-butyl 3-(2-(3-methoxyphenyl)acetyl)-4-oxopiperidine-1-carboxylate and 1-(4-(2-methyl-1H-imidazol-1-yl)phenyl)guanidine (Example 41c) according to the general procedure for synthesis of pyrimidines. MS (ES+) m/z 527.1 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188101B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-351d8874714c46239eef7776bb9c7232 |
| Source note | uspto-grants-2012_05 |