Glycolaldehyde → HCID 46199110, compound

Participants

Reaction Steps

2-(4-(2-Fluorobenzyl)-2-(4-(2-methyl-1H-imidazol-1-yl)phenylamino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)ethanol (4.7 mg, 4.5%) was synthesised from 4-(2-fluorobenzyl)-N-(4-(2-methyl-1H-imidazol-1-yl)phenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine (Example 52a) and glycolaldehyde according to the general procedure for reductive amination. MS (ES+) m/z 459.3 (M+H)+

Provenance & Evidence