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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1930630Generated: October 30, 2026

Tetrahydro-4H-pyran-4-one → 3-(2-Methoxy-2-phenylacetyl)dihydro-2H-pyran-4(3H)-one

https://huagongshe.com/reaction/1930630

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydro-4H-pyran-4-oneHCID 121599—
Reactant2-Methoxy-2-phenylacetyl chlorideHCID 12635955—
Product3-(2-Methoxy-2-phenylacetyl)dihydro-2H-pyran-4(3H)-oneHCID 5933369214.5%

Reaction Steps

3-(2-Methoxy-2-phenylacetyl)dihydro-2H-pyran-4(3H)-one (54 mg, 14.5%) was synthesised from 2-methoxy-2-phenylacetyl chloride and dihydro-2H-pyran-4(3H)-one according to the general procedure for the preparation of diketones. MS (ES−) m/z 247.1 (M−H)−

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188101B2
Source datasetuspto-grants-2012_05
ORD IDord-5f077bf3e1df43ba99accda24ebe9d25
Source noteuspto-grants-2012_05