反应详情

温度

80 °C

tert-Butyl 4-(ethyl((tetrahydrofuran-2-yl)methyl)amino)-2-(4-(oxazol-5-yl)phenylamino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate (320 mg, 0.61 mmol) was dissolved in methanol (5 mL). Hydrochloric acid (0.019 mL, 0.61 mmol) was added and the reaction mixture was stirred at 80° C. for 1 h. The solvent was evaporated under reduced pressure and the crude was used as such in the subsequent step. MS (ES+) m/z 421.0 (M+H)+

1. customThe solvent was evaporated under reduced pressure