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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1930670Generated: October 30, 2026

Hydrochloric Acid → HCID 59333775, compound

https://huagongshe.com/reaction/1930670

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 59333740HCID 59333740—
SolventMethanolHCID 887—
ProductHCID 59333775HCID 59333775—

Reaction Conditions

Temperature75 °C

Reaction Steps

(S)-tert-Butyl 2-(4-(oxazol-5-yl)phenylamino)-4-((tetrahydrofuran-2-yl)methylamino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate was dissolved in methanol (3 mL). Hydrochloric acid was added and the reaction mixture was stirred at 75° C. for 1 h. The solvent was evaporated under reduced pressure and the crude was used as such in the next step. MS (ES+) m/z 393.2 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188101B2
Source datasetuspto-grants-2012_05
ORD IDord-94ac3f8298524795ba7c89948d7d2e6e
Source noteuspto-grants-2012_05