HRID1930675
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
CONDITIONS
反应条件
- 温度
- 80 °C
PROCEDURE
实验过程
tert-Butyl 2-(4-(oxazol-5-yl)phenylamino)-4-(trifluoromethylsulfonyloxy)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate (350 mg, 0.65 mmol, example 1b) was dissolved in DMF (2 mL). 4-Aminomethyltetrahydropyran (74.4 mg, 0.65 mmol) was added and the reaction mixture was stirred at 80° C. for 6 h. The solvent was evaporated under reduced pressure and the crude was used in the next step as such. MS (ES+) m/z 507.3 (M+H)+
WORKUP
后处理
- customThe solvent was evaporated under reduced pressure