Thionyl Chloride → 2-(2-Fluorophenyl)acetyl chloride

Participants

Reaction Steps

2-(2-Fluorophenyl)acetic acid, (1.7 mmol) was dissolved in thionyl chloride (0.372 ml, 5.10 mmol) and heated to reflux for 1 h. The reaction was cooled and the excess thionyl chloride was evaporated. The residue was instantly dissolved in dry THF and refridgerated until used. No purity analysis or weighing were performed.

Provenance & Evidence