反应详情

温度

80 °C

tert-Butyl 4-benzyl-2-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenylamino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate (1.0 g, 1.90 mmol) was dissolved in methanol (10 mL). Hydrochloric acid (0.156 mL, 1.90 mmol) was added and the reaction mixture was stirred at 80° C. for 1 h. The solvent was evaporated under reduced pressure and the crude was used in the subsequent step as such. MS (ES+) m/z 427.0 (M+H)+

1. customThe solvent was evaporated under reduced pressure