Phenylacetyl chloride → HCID 59333797, compound

HRID 1930733Notes

Reaction equation

[C:1]1([CH2:7][C:8](Cl)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[S:11]1[CH2:16][CH2:15][C:14](=[O:17])[CH2:13][CH2:12]1>>[C:1]1([CH2:7][C:8]([CH:13]2[C:14](=[O:17])[CH2:15][CH2:16][S:11][CH2:12]2)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

Reactant 2

HCID 7679Phenylacetyl chloride

HCID 66173Tetrahydrothiopyran-4-one

Product 1

HCID 59333797HCID 59333797, compoundYield 83%

Procedure

3-(2-Phenylacetyl)dihydro-2H-thiopyran-4(3H)-one (291 mg, 83%) was synthesised from 2-phenylacetyl chloride and dihydro-2H-thiopyran-4(3H)-one according to the general procedure for the preparation of diketones. MS (ES−) m/z 233 (M−H)−

Sources & evidence

ORD record: ord-2c1c1d34a831448aa3688a8620b8f1df
Source dataset: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08188101B2

Reaction notes

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