Trifluoroacetic acid → HCID 57753638, compound

HRID 1930831Notes

Reaction equation

HRID 1930831 reaction equation
[F:1][C:2]1[CH:10]=[C:9]([C:11]([F:14])([F:13])[F:12])[CH:8]=[C:7]2[C:3]=1[CH2:4][N:5](C(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[CH2:6]2.FC(F)(F)C(O)=O>>[F:1][C:2]1[CH:10]=[C:9]([C:11]([F:14])([F:13])[F:12])[CH:8]=[C:7]2[C:3]=1[CH2:4][NH:5][CH2:6]2

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 57753565HCID 57753565, compound

Product 1

HCID 57753638HCID 57753638, compound

Procedure

Prepared in analogy to Example A2 (c) from 4-Fluoro-6-trifluoromethyl-2-trityl-2,3-dihydro-1H-isoindole and trifluoroacetic acid. Yellow oil. MS (m/e): 206.1 ([M+H+, 100%).

Sources & evidence

ORD record
ord-dcbe0add171e495c9cc9f2168c9289e9
Source dataset
uspto-grants-2012_05
Patent number
US08188139B2

Reaction notes

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